Author: btp.lab@gmail.com

  • Seamus Mellican, PhD Student

    Seamus Mellican, PhD Student

    Seamus is conducting his PhD study in Mechanical Science and Engineering at the University of Illinois Urbana-Champaign. He gradudated with BS in Mechanical Engineering from the University of Illinois. His research regards the PDAC-liver interaction using microfluidics and 3D printing techniques.

  • Ali Aykut Akalin, PhD Student

    Ali Aykut Akalin, PhD Student

    Ali is conducting his PhD study in Mechanical Sceince and Engineering at the University of Illinos Urbana-Champaign. He graduated from Middle Eastern Technical University (METU) in Turkiye with his BS and MS degrees in Mechanical Engineering. His research regards neuroinflammation and brain transport MPS models.

  • Anthony Mercader, Postdoc Fellow

    Anthony Mercader, Postdoc Fellow

    Anthony is a Postdoc Fellow in Mechanical Science and Engineering. He received his Ph.D. in Mechanical Engineering from the University of Pittsburgh.  He performs experimental research to develop and test microfluidic physiology models of cancers and brain diseases for drug discovery and biology research. Specifically, he will work on developing microfluidics platforms perfused with human…

  • Disclaimer

    Posts under “PI’s blog” are the personal views, opinions and thoughts of the Principal Investigator on various topics. These posts do not reflect the view of the group members, Department, University and Funding Agencies.

  • CZ Biohub Chicago

    CZ Biohub Chicago

    Bumsoo Han is selected as a Chan Zukerberg Biohub Investigator at CZ Biohub Chicago. We will study the neuroinflammation mechanisms using engineered tissue models. Specifically, we are investigating the effects of disrupted blood-brain interface and circadian rhythm in neuroinflammation through collaboration with Martha Gillette’s lab. CZ Biohub Investigator Page MechSE News Release

  • Andrew Mugler Seminar at UIUC

    Andrew Mugler Seminar at UIUC

    Professor Andrew Mugler of Physics from the University of Pittsburg visited the lab. We have been collaborating with his lab to understand the biophysics of cancer cell chemotaxis. Our collaboration is extended to understand cellular sensing and information processing of chemical and flow cues.

  • Altug Visits UIUC

    Altug Visits UIUC

    Professor Altug Ozcelikkale, our Alumnus, from the Middle Eastern Technical University at Turkiye visited our group. He completed his PhD study in the group in 2015 and performed his Postdoc research until 2017. He is currently directing the Engineered Biomicrosystems Laboratory to develop engineered biomicrosystems for high-fidelity modeling of human physiology in health and disease.

  • Conductive Hydrogel

    Conductive Hydrogel

    A collaborative paper with Dr. Tian Li’s lab at Purdue University is published in the Journal Cell Reports Physical Science as below: Conductive hollow hydrogel fibers toward high-sensitivity bio-textiles Pengfei Deng, Zijian He, Yingnan Shen, Noor Mohammad Mohammad, Wenhui Xu, Bumsoo Han and Tian Li Abstract Conductive hydrogels are becoming valuable in creating soft, flexible…

  • Sae Rome successfully defended her PhD dissertation

    Sae Rome successfully defended her PhD dissertation

    Sae Rome successfully defended her PhD dissertation, entitled “Reprogramming the pancreatic cancer stroma by targeting coagulation at the tumor microenvironment.” In this work, she developed microphysiological model of PDAC stroma with controlled coagulation system, and investigated the role of the extravascular coagulation system in tumor progression, tumor-associated fibrosis and drug resistance. Through her research, she…

  • Move to UIUC

    Move to UIUC

    Our group joins the Department of Mechanical Science and Engineering at the University of Illinois Urbana-Champaign, and starts the Cellular and Molecular Transport Laboratory, after successful 14 years of Biotransport Phenomena Laboratory at Purdue University. We will also participate in the Cancer Center at Illinois, Materials Research Laboratory, Institutional Genomic Biology and Beckman Institute. We…

  • Drug Discovery using 3D Tumor Models

    Drug Discovery using 3D Tumor Models

    A collaborative paper with Dr. Melissa Fishel’s Group at Indiana University was published in the Journal Pharmacological Research as below. New Ref-1/APE1 targeted inhibitors demonstrating improved potency for clinical applications in multiple cancer types Silpa Gampala, Hye-ran Moon, Randall Wireman, Jacqueline Peil, Sonia Kiran, Dana K Mitchell, Kylee Brewster, Henry Mang, Andi Masters, Christine Bach,…

  • Nanoparticle Manufacturing

    Nanoparticle Manufacturing

    Our paper regarding nanoparticle manufacutring using microfluidics are published in the Journal Analyst. The paper is selected as Cover Article and also selected for Analyst Review Articles 2023. Advanced manufacturing of nanoparticle formulations of drugs and biologics using microfluidics Yingnan Shen, Hogyeong Gwak and Bumsoo Han Abstract Numerous innovative nanoparticle formulations of drugs and biologics,…