A collaborative paper with Professor Andrew Mugler’s group in Physics is published in Biophysical Journal, and the result is highlighted at the Journal website (Video). Collective Chemotaxis through Noisy Multicellular Gradient Sensing Julien Varennes, Bumsoo Han, Andrew Mugler Abstract Collective cell migration in response to a chemical cue occurs in many biological processes such …
A collaborative review on in vitro tumor models using microfluidics and tissue engineering is published in Cancer Letters. Recapitulation of complex transport and action of drugs at the tumor microenvironment using tumor-microenvironment-on-chip Bumsoo Han, Chunjing Qu, Kinam Park, Stephen F. Konieczny, Murray Korc Abstract: Targeted delivery aims to selectively distribute drugs to targeted tumor tissues …
Our work to characterize cellular pharmacokinetics (i.e., drug uptake) using tumor-microenvironment-on-chip and quantitative microscopy is published in Molecular Pharmaceutics. Corresponding news release can also be found here. Characterization of Cell-Type-Specific Drug Transport and Resistance of Breast Cancers Using Tumor-Microenvironment-on-Chip Kyeonggon Shin, Brett S. Klosterhoff, and Bumsoo Han Abstract: Heterogeneous response and resistance of …
A collaborative paper with Professor Jong Choi’s group using DNA walker as a new drug delivery system is accepted for publication in the Journal ChemBioChem. DNA Walker-Regulated Cancer Cell Growth Inhibition Feiran Li, Tae-Gon Cha, Jing Pan, Altug Ozcelikkale, Bumsoo Han, and Jong Hyun Choi Abstract: We use a DNAzyme-based walker system as …
Thermal Destabilization of Collagen Matrix Hierarchical Structure by Freeze/Thaw Altug Ozcelikkale, and Bumsoo Han Abstract: This study aims to characterize and understand the effects of freezing on collagen structures and functionality. Specifically, thermodynamic destabilization of collagen at molecular- and fibril-levels by combination of low temperatures and freezing were experimentally characterized using modulated differential scanning calorimetry. …
Read more “Freezing-induced structural change of collagen is published at PLoS One.”
Dropwise gelation-dehydration kinetics during drop-on-demand printing of hydrogel-based materials Bumsoo Han, Gyu Young Yun, J. William Boley, Samuel Haidong Kim, Jun Young Hwang, George T.-C. Chiu and Kinam Park Abstract: The present study aims to characterize and understand the dropwise gelation-dehydration phenomena during drop-on-demand (DOD) printing of hydrogel-based soft materials. Functional soft materials have broader impacts …
Read more “3D printing of hydrogel is published at Int J Heat Mass.”
List of publications until 2015 L. Shi, C. Dames, J. R. Lukes, P. S. Reddy, J. Duda, D. G. Cahill, J. Lee, A. Marconnet, K. E. Goodson, J.-H. Bahk, A. Shakourij, R. S. Prasher , J. Felts, W. P. King, B. Han, and J. C. Bischof, 2015, “Evaluating broader impacts of nanoscale thermal transport,” Nanoscale and …