New Members in Fall 2016

Anna Zhuang starts her PhD study from this fall.  Anna is not totally new, and has been performing research in the group via SURF from the College of Engineering, and Bottomley Undergraduate Research Scholarship from the School of Mechanical Engineering. Jingyi Qin also joins the group for her undergraduate research.

Cellular Poroelasticity during Freezing

Our work regarding cytoplasmic fluid-structure interaction during cryopreservation of cells and engineered tissues is published in the Journal of the Royal Society Interface. Role of intracellular poroelasticity on freezing-induced deformation of cells in engineered tissues Soham Ghosh, Altug Ozcelikkale, J. Craig Dutton, Bumsoo Han Abstract Freezing of biomaterials is important in a wide variety of …

2016 Hawkins Lecture: Suhas Patankar

Professor Suhas Patankar from the University of Minnesota, 2016 Hawkins Lecturer because of his contribution to computational heat transfer, visited Purdue from 9/21-23 and delivered talks about his research on cooling data center.  Professor Patankar was Han’s instructor of “Numerical Heat Transfer” when he was a PhD student at the University of Minnesota.

Cell adhesion and migration on nanopetal

A collaborative paper with Professor Tim Fisher’s group on adhesion and migration of cells on graphitic nanopetal structures is published in Materials Letters. Guidance of cell adhesion and migration by graphitic nanopetals on carbon fibers Soham Ghosh, Guoping Xiong, Timothy S. Fisher and Bumsoo Han Abstract Carbon-based nanomaterials have emerged in a wide variety of applications because of …

Simulation of Collective Chemotaxis

A collaborative paper with Professor Andrew Mugler’s group in Physics is published in Biophysical Journal, and the result is highlighted at the Journal website (Video).   Collective Chemotaxis through Noisy Multicellular Gradient Sensing Julien Varennes, Bumsoo Han, Andrew Mugler Abstract Collective cell migration in response to a chemical cue occurs in many biological processes such …

Special Issue of ACS Molecular Pharmaceutics

A special issue of ACS Molecular Pharmaceutics, entitled “Physics-Inspired Micro/Nanotherapeutics: Same Problem, Different Approaches,” is now available here.  Han is the Guest Editor of the issue.

Review on tumor-microenvironment-on-chip

A collaborative review on in vitro tumor models using microfluidics and tissue engineering is published in Cancer Letters. Recapitulation of complex transport and action of drugs at the tumor microenvironment using tumor-microenvironment-on-chip Bumsoo Han, Chunjing Qu, Kinam Park, Stephen F. Konieczny, Murray Korc Abstract: Targeted delivery aims to selectively distribute drugs to targeted tumor tissues …

Cellular Pharmacokinetics using T-MOC

Our work to characterize cellular pharmacokinetics (i.e., drug uptake) using tumor-microenvironment-on-chip and quantitative microscopy is published in Molecular Pharmaceutics.   Corresponding news release can also be found here.   Characterization of Cell-Type-Specific Drug Transport and Resistance of Breast Cancers Using Tumor-Microenvironment-on-Chip Kyeonggon Shin, Brett S. Klosterhoff, and Bumsoo Han   Abstract: Heterogeneous response and resistance of …

Victoria Noe-Kim

Victoria was an undergraduate research assistant (2011-2013) in the Han Group.  She moved to the National Institutes of Health for a Research Fellowship. [ap_social facebook=”” twitter=”” gplus=”” linkedin=”https://www.linkedin.com/in/victoria-noe-kim-a6356934/” dribble=””]

Drug delivery using DNA walker

A collaborative paper with Professor Jong Choi’s group using DNA walker as a new drug delivery system is accepted for publication in the Journal ChemBioChem.     DNA Walker-Regulated Cancer Cell Growth Inhibition Feiran Li, Tae-Gon Cha, Jing Pan, Altug Ozcelikkale, Bumsoo Han, and Jong Hyun Choi Abstract: We use a DNAzyme-based walker system as …