Hye-ran’s paper on directed cell migration with Andrew Mugler’s group is published on the Journal Lab on a Chip. It is also selected as Lab on a Chip HOT Article 2023. In this work, Hye-ran proposed model migrating cancer cells as digital logic gates to process entangled chemical and fluidic microenvironmental cues. Cells function as …
Our work on microfluidic tumor models of subtype-specific triple-negative breast cancer is published at the Journal PlosONE. Subtype-specific characterization of breast cancer invasion using a microfluidic tumor platformHye-ran Moon, Natalia Ospina-Muñoz, Victoria Noe-Kim, Yi Yang, Bennett D. Elzey, Stephen F. Konieczny, and Bumsoo Han AbstractUnderstanding progression of breast cancers to invasive ductal carcinoma (IDC) can …
Mike and Stephanie’s work regarding PDAC tumor model is published at the Journal “Small.” This paper aims to create an in vitro tumor model reconstituting intratumoral heterogeneity of human pancreatic cancer. This work is based on collaboration with Professor Konieczny’s group in the Department of Biological Science at Purdue. A Biomimetic Tumor Model of …